Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 9/20 | 0.70 |
| ▸ | CYSLTR2 | Q9NS75 | 8/20 | 0.70 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.63 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.59 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870875 | 0.86 | ALOX5 (0.61) | CYSLTR1CYSLTR2ALOX5HDAC6GPBAR1 | |
| SCHEMBL14021599 | 0.82 | CYSLTR1 (1.00) | CYSLTR1CYSLTR2ALOX5HDAC6GPBAR1 | |
| Bicarbonate SCHEMBL9374712 | 0.81 | CYSLTR1 (0.72) | CYSLTR1CYSLTR2ALOX5HDAC6GPBAR1 | |
| SCHEMBL10547998 | 0.80 | CYSLTR1 (1.00) | CYSLTR1CYSLTR2GPBAR1FFAR1AKR1B1 | |
| SCHEMBL1793731 | 0.80 | CYSLTR1 (0.74) | CYSLTR1CYSLTR2ALOX5HDAC6GPBAR1 | |
| SCHEMBL9556595 | 0.80 | ALOX5 (0.71) | ALOX5HDAC6GPBAR1 | |
| SCHEMBL7752019 | 0.79 | ALOX5 (0.71) | ALOX5HDAC6 | |
| SCHEMBL8965425 | 0.79 | CYSLTR1 (0.64) | CYSLTR1CYSLTR2ALOX5HDAC6GPBAR1 | |
| SCHEMBL9137219 | 0.79 | GPBAR1 (0.67) | CYSLTR1CYSLTR2ALOX5HDAC6GPBAR1 | |
| SCHEMBL9474669 | 0.78 | ALOX5 (0.64) | CYSLTR1CYSLTR2ALOX5HDAC6GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342510-B1 | ANTIINFLAMMATORY AGENTS AND ENZYME INHIBITORS | G. D. SEARLE & CO. | 2002-01-29 | — | — | US | disclosed |