Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | GUSB | P08236 | 5/20 | 0.63 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7692642 | 0.89 | ALDH1A1 (0.78) | ALDH1A1GUSBGAAKDM4ENPC1 | |
| SCHEMBL10112940 | 0.85 | ALDH1A1 (0.71) | ALDH1A1GUSBGAAKDM4ENPC1 | |
| SCHEMBL7694808 | 0.82 | ALDH1A1 (0.55) | ALDH1A1GUSBGAAKDM4EMAPT | |
| SCHEMBL7690400 | 0.79 | ALDH1A1 (0.56) | ALDH1A1GUSBGAAKDM4ENPC1 | |
| SCHEMBL7689750 | 0.79 | ALDH1A1 (0.70) | ALDH1A1GUSBGAAKDM4ENPC1 | |
| SCHEMBL7694827 | 0.78 | ALDH1A1 (0.61) | ALDH1A1GUSBGAAKDM4EMAPT | |
| SCHEMBL10113654 | 0.78 | GUSB (1.00) | ALDH1A1GUSBKDM4ECYP2C19 | |
| SCHEMBL7690425 | 0.77 | ALDH1A1 (0.63) | ALDH1A1GUSBGAAKDM4ENPC1 | |
| SCHEMBL28562281 | 0.74 | DHFR (0.77) | ALDH1A1GUSBGAAKMT2A | |
| SCHEMBL10280173 | 0.73 | ALDH1A1 (0.65) | ALDH1A1GUSBGAAKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002066443-A2 | 2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-08-29 | — | — | WO | disclosed |