Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5594535 | 0.88 | RAD52 (0.45) | RAD52THRBL3MBTL1TDP1ATM | |
| SCHEMBL5594212 | 0.87 | ALDH1A1 (0.39) | L3MBTL1TDP1ATMKDM4EALDH1A1 | |
| SCHEMBL28989675 | 0.79 | TSHR (0.45) | RAD52THRBL3MBTL1TDP1KDM4E | |
| SCHEMBL28989837 | 0.78 | TSHR (0.48) | RAD52THRBTDP1KDM4EALDH1A1 | |
| SCHEMBL15751387 | 0.78 | TSHR (0.48) | RAD52THRBTDP1KDM4EALDH1A1 | |
| SCHEMBL8065282 | 0.77 | THRB (0.46) | RAD52THRBL3MBTL1TDP1KDM4E | |
| SCHEMBL12383183 | 0.76 | ALDH1A1 (0.41) | L3MBTL1TDP1ATMKDM4EALDH1A1 | |
| SCHEMBL13801028 | 0.76 | TDP1 (0.36) | THRBL3MBTL1TDP1ATMKDM4E | |
| SCHEMBL18906414 | 0.75 | EDNRA (0.40) | L3MBTL1TDP1ATMKDM4EALDH1A1 | |
| SCHEMBL13801030 | 0.75 | TDP1 (0.40) | THRBL3MBTL1TDP1ATMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6344654-B1 | AN ETHYLENICALLY UNSATURATED MONOMER IS COPOLYMERIZED WITH A POLYNUCLEAR AROMATIC HYDROCARBON OR A SUBSTITUTED AROMATIC DERIVATIVE THEREOF, SUCH THAT THE RESULTANT POLYMER IS FLUORESCENT. | ROHM AND HAAS COMPANY | 2002-02-05 | — | — | US | claimed |