SCHEMBL7698399

SCHEMBL7698399

C=C(C)C(=O)OCCc1ccc(N(C)C)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.45
ALDH1A1 P00352 8/20 0.42
HPGD P15428 5/20 0.42
TSHR P16473 4/20 0.42
MAPK1 P28482 4/20 0.42
NPC1 O15118 4/20 0.42
KDM4E B2RXH2 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
GAA P10253 1/20 0.42
HSD17B10 Q99714 1/20 0.42
CNR2 P34972 1/20 0.42
MAPT P10636 6/20 0.41
CALM1 P0DP23 2/20 0.41
TDP1 Q9NUW8 2/20 0.40
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40
CYP3A4 P08684 1/20 0.40
HDAC1 Q13547 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14981546 0.89 THRB (0.50) THRBALDH1A1TSHRNPC1SMN1; SMN2
SCHEMBL11921516 0.88 THRB (0.55) THRBALDH1A1HPGDTSHRMAPK1
SCHEMBL14123735 0.88 THRB (0.42) THRBALDH1A1HPGDTSHRMAPK1
SCHEMBL2602558 0.88 THRB (0.49) THRBALDH1A1TSHRNPC1SMN1; SMN2
SCHEMBL22566492 0.87 THRB (0.53) THRBALDH1A1HPGDTSHRMAPK1
SCHEMBL13839846 0.85 THRB (0.46) THRBTSHRNPC1SMN1; SMN2CNR2
SCHEMBL2602559 0.85 THRB (0.46) THRBALDH1A1TSHRNPC1SMN1; SMN2
SCHEMBL1468923 0.84 ALDH1A1 (0.55) ALDH1A1HPGDTSHRMAPK1NPC1
SCHEMBL9915741 0.84 THRB (0.45) THRBTSHRTDP1POLBAPEX1
SCHEMBL21880709 0.84 THRB (0.45) THRBALDH1A1HPGDTSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100494278-C Precusor solution of polyimide/silicon oxide composite its preparation process and manufactured composite material CHANGXING CHEMICAL INDUSTRY CO (CN) 2009-06-03 CN claimed
CN-1693367-A Forward solution of polyimide/silicon oxide composite its preparation process and manufactured composite from same CHANGXING CHEMICAL INDUSTRY CO (CN) 2005-11-09 CN claimed
CN-100494278-C Precusor solution of polyimide/silicon oxide composite its preparation process and manufactured composite material CHANGXING CHEMICAL INDUSTRY CO (CN) 2009-06-03 CN disclosed
CN-1693367-A Forward solution of polyimide/silicon oxide composite its preparation process and manufactured composite from same CHANGXING CHEMICAL INDUSTRY CO (CN) 2005-11-09 CN disclosed
US-6348429-B1 POLYMERIZATION INITIATOR OF HIGH MOLECULAR WEIGHT DIACYL PEROXIDE AND TERTIARY AMINE; CEMENTS FOR BIOMEDICAL EQUIPMENT, ORTHOPEDICS, DENTISTRY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2002-02-19 US disclosed
EP-0758268-A4 POLYMER CEMENT COMPOSITIONS AND INITIATORS FOR USE IN THE PREPARATION THEREOF UNIV CALIFORNIA (US) 1999-04-28 EP disclosed
EP-0758268-A1 POLYMER CEMENT COMPOSITIONS AND INITIATORS FOR USE IN THE PREPARATION THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1997-02-19 EP disclosed
WO-1995030480-A2 INITIATORS OF TERTIARY AMINE/PEROXIDE AND POLYMER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1995-11-16 WO disclosed