Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 7/20 | 0.66 |
| ▸ | PDE4D | Q08499 | 15/20 | 0.58 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6836821 | 0.99 | PDE4A (0.65) | PDE4APDE4DPDE4BPDE3BPDE3A | |
| SCHEMBL5751710 | 0.99 | PDE4A (0.65) | PDE4APDE4DPDE4BPDE3BPDE3A | |
| SCHEMBL14456335 | 0.94 | PDE4A (0.59) | PDE4APDE4DPDE4BPDE3BPDE3A | |
| SCHEMBL4565777 | 0.92 | PDE4A (0.78) | PDE4APDE4DPDE4BPDE3BPDE3A | |
| SCHEMBL3304195 | 0.92 | PDE4A (0.77) | PDE4APDE4DPDE4BPDE3BPDE3A | |
| SCHEMBL3299351 | 0.91 | PDE4A (0.62) | PDE4APDE4DPDE4BPDE3BPDE3A | |
| SCHEMBL3304549 | 0.91 | PDE4A (0.62) | PDE4APDE4DPDE4BPDE3BPDE3A | |
| SCHEMBL13395949 | 0.89 | PDE4A (0.60) | PDE4APDE4DPDE4BPDE3BPDE3A | |
| SCHEMBL6837875 | 0.89 | PDE4D (0.63) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL3305166 | 0.88 | PDE4A (0.59) | PDE4APDE4DPDE4BPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090012051-A1 | EXTERNAL PREPARATION | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-01-08 | — | — | US | claimed |
| US-20060239927-A1 | Drug for airway administration | KYOWA HAKKO KOGYO CO., (JP) | 2006-10-26 | — | — | US | claimed |
| US-20060205749-A1 | Remedy and/or preventive for lung diseases | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-09-14 | — | — | US | claimed |
| US-20060199789-A1 | medical composition | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-09-07 | — | — | US | claimed |
| US-20060173028-A1 | Therapeutic and/or preventive agent for chronic skin disease | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-08-03 | — | — | US | claimed |
| EP-1634606-A1 | DRUG FOR AIRWAY ADMINISTRATION | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-03-15 | — | — | EP | claimed |
| EP-1621196-A1 | THERAPEUTIC AND/OR PREVENTIVE AGENT FOR CHRONIC SKIN DISEASE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-02-01 | — | — | EP | claimed |
| EP-1616569-A1 | MEDICINAL COMPOSITION | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-01-18 | — | — | EP | claimed |
| EP-1609471-A1 | REMEDY AND/OR PREVENTIVE FOR LUNG DISEASES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2005-12-28 | — | — | EP | claimed |
| WO-2023203022-A1 | TREATMENT OF NEUTROPHILIC DERMATOSES | UNION therapeutics A/S (DK) | 2023-10-26 | — | — | WO | disclosed |
| CN-108368094-B | Non-steroidal glucocorticoid receptor modulators for topical drug delivery | 利奥制药有限公司 | 2021-07-02 | — | — | CN | disclosed |
| US-10994082-B2 | Inhaler counter | ASTRAZENECA AB (SE) | 2021-05-04 | — | — | US | disclosed |
| EP-3350175-B1 | NON-STEROIDAL GLUCOCORTICOID RECEPTOR MODULATORS FOR LOCAL DRUG DELIVERY | LEO PHARMA AS (DK) | 2019-11-06 | — | — | EP | disclosed |
| US-20190175849-A1 | INHALER COUNTER | BANG & OLUFSEN MEDICOM A/S (DK) | 2019-06-13 | — | — | US | disclosed |
| WO-2004087147-A1 | REMEDY AND/OR PREVENTIVE FOR LUNG DISEASES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-10-14 | — | — | WO | disclosed |
| WO-2004082683-A1 | THERAPEUTIC AND/OR PREVENTIVE AGENT FOR CHRONIC SKIN DISEASE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-09-30 | — | — | WO | disclosed |
| US-6716987-B1 | PHOSPHODIESTERASE IV INHIBITORS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-04-06 | — | — | US | disclosed |
| US-6514996-B2 | Derivatives of benzofuran or benzodioxole | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-02-04 | — | — | US | disclosed |
| US-20020128290-A1 | DERIVATIVES OF BENZOFURAN OR BENZODIOXOLE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-09-12 | — | — | US | disclosed |
| EP-0771794-A1 | OXYGEN-CONTAINING HETEROCYCLIC COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-05-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128290-A1 | DERIVATIVES OF BENZOFURAN OR BENZODIOXOLE | CBR1, CBR3, CYC1 | PDE4A 4879/4885PDE4D 4870/4885PDE4B 4877/4885 |
| US-20060205749-A1 | Remedy and/or preventive for lung diseases | MPO, ELANE, MMP8 | PDE4A 806/4885PDE4D 1967/4885PDE4B 1051/4885 |
| US-20060199789-A1 | medical composition | NR3C2, CYP11B2, CYP11B1 | PDE4A 149/4885PDE4D 503/4885PDE4B 152/4885 |
| US-20060239927-A1 | Drug for airway administration | PDE12, PDE4A, PDE4B | PDE4A 2/4885PDE4D 7/4885PDE4B 3/4885 |
| US-20090012051-A1 | EXTERNAL PREPARATION | CYP4A11, CYP46A1, CYP11B2 | PDE4A 406/4885PDE4D 514/4885PDE4B 423/4885 |
| US-20060173028-A1 | Therapeutic and/or preventive agent for chronic skin disease | SERPINB1, CYP24A1, MMP8 | PDE4A 616/4885PDE4D 951/4885PDE4B 963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.