Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CTRC | Q99895 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | PLG | P00747 | 1/20 | 0.30 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
| ▸ | PLAT | P00750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7124429 | 1.00 | DRD1 (0.32) | DRD1SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL7126456 | 0.84 | CYP3A4 (0.34) | CTRCF2PLGPLAUPLAT | |
| SCHEMBL7121195 | 0.84 | CYP3A4 (0.34) | CTRCF2PLGPLAUPLAT | |
| SCHEMBL7508213 | 0.76 | MTNR1A (0.42) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7121703 | 0.76 | MTNR1A (0.42) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7127061 | 0.76 | ALDH1A1 (0.31) | — | |
| SCHEMBL7619728 | 0.71 | CYP3A4 (0.37) | SLC6A2SLC6A4SLC6A3HTR2CHTR2B | |
| SCHEMBL576223 | 0.69 | THRB (0.40) | — | |
| SCHEMBL8656840 | 0.67 | MAOB (0.43) | — | |
| SCHEMBL8658724 | 0.67 | MAOB (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350775-B1 | AGAINST GRAMPOSITIVE BACTERIA | ZENECA LIMITED (GB) | 2002-02-26 | — | — | US | disclosed |