Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 18/20 | 0.54 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 11/20 | 0.53 |
| ▸ | MMP2 | P08253 | 6/20 | 0.53 |
| ▸ | MMP3 | P08254 | 17/20 | 0.53 |
| ▸ | MMP7 | P09237 | 15/20 | 0.53 |
| ▸ | MMP13 | P45452 | 14/20 | 0.53 |
| ▸ | MMP8 | P22894 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7508761 | 0.88 | MMP13 (0.50) | MMP1ADAM17MMP9MMP2MMP3 | |
| SCHEMBL7510882 | 0.85 | MMP1 (0.57) | MMP1ADAM17MMP9MMP2MMP3 | |
| SCHEMBL7442655 | 0.85 | MMP1 (0.57) | MMP1ADAM17MMP9MMP2MMP3 | |
| SCHEMBL7503957 | 0.83 | MMP9 (0.53) | MMP1ADAM17MMP9MMP2MMP3 | |
| SCHEMBL7529490 | 0.80 | MMP13 (0.55) | MMP1ADAM17MMP9MMP2MMP3 | |
| SCHEMBL7505164 | 0.79 | MMP1 (0.58) | MMP1ADAM17MMP9MMP2MMP3 | |
| SCHEMBL7618861 | 0.76 | MMP1 (0.54) | MMP1ADAM17MMP9MMP2MMP3 | |
| SCHEMBL7509176 | 0.76 | MMP1 (0.51) | MMP1ADAM17MMP9MMP2MMP3 | |
| SCHEMBL7510461 | 0.75 | MMP13 (0.53) | MMP1ADAM17MMP9MMP2MMP3 | |
| SCHEMBL7505801 | 0.72 | MMP13 (0.50) | MMP1ADAM17MMP9MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342508-B1 | ENZYME INHIBITORS FOR PROTECTION OF CONNECTIVE TISSUES | AMERICAN CYANAMID COMPANY | 2002-01-29 | — | — | US | disclosed |