Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 18/20 | 0.39 |
| ▸ | MMP1 | P03956 | 17/20 | 0.39 |
| ▸ | MMP9 | P14780 | 10/20 | 0.39 |
| ▸ | MMP2 | P08253 | 13/20 | 0.36 |
| ▸ | MMP7 | P09237 | 5/20 | 0.36 |
| ▸ | MMP8 | P22894 | 3/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | MMP14 | P50281 | 2/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.36 |
| ▸ | MMP20 | O60882 | 1/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | MMP10 | P09238 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | MMP15 | P51511 | 1/20 | 0.36 |
| ▸ | MMP16 | P51512 | 1/20 | 0.36 |
| ▸ | MMP25 | Q9NPA2 | 1/20 | 0.36 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.36 |
| ▸ | MMP24 | Q9Y5R2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697149 | 1.00 | MMP3 (0.39) | MMP3MMP1MMP9MMP2MMP7 | |
| SCHEMBL7697152 | 1.00 | MMP3 (0.39) | MMP3MMP1MMP9MMP2MMP7 | |
| SCHEMBL27410744 | 0.81 | MMP3 (0.34) | MMP3MMP1MMP9MMP2MMP7 | |
| SCHEMBL23371280 | 0.78 | HDAC7 (0.37) | MMP3MMP1MMP9MMP2MMP7 | |
| SCHEMBL9962280 | 0.78 | POLB (0.39) | MMP3MMP2 | |
| SCHEMBL26665913 | 0.76 | MAPT (0.32) | MMP3MMP1MMP9 | |
| SCHEMBL28976649 | 0.76 | PTGS1 (0.31) | — | |
| SCHEMBL14602776 | 0.75 | PTGS1 (0.58) | MMP3MMP1MMP9MMP2MMP7 | |
| SCHEMBL10051718 | 0.75 | PTGS1 (0.58) | MMP3MMP1MMP9MMP2MMP7 | |
| SCHEMBL19845930 | 0.74 | MMP1 (0.36) | MMP3MMP1MMP9MMP2MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348612-B1 | FORM COMPLEXES USED AS CATALYSTS FOR ENANTIOSELECTIVE REACTIONS SUCH AS ASYMMETRIC HYDROGENATIONS, ENANTIOSELECTIVE HYDROGEN DISPLACEMENTS, ALLYLIC SUBSTITUTION REACTIONS | ROCHE VITAMINS INC. | 2002-02-19 | — | — | US | disclosed |
| EP-0864576-A1 | Novel amidophospine-phosphinite derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1998-09-16 | — | — | EP | disclosed |