Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 5/20 | 0.45 |
| ▸ | DRD2 | P14416 | 4/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1907944 | 0.82 | S1PR1 (0.55) | SIGMAR1DRD4DRD2DPP7BACE1 | |
| SCHEMBL17294922 | 0.80 | S1PR1 (0.53) | SIGMAR1DRD4DRD2DPP7BACE1 | |
| SCHEMBL429257 | 0.78 | MTNR1A (0.77) | MTNR1AMTNR1BKMT2A | |
| SCHEMBL20183285 | 0.77 | DRD4 (0.70) | SIGMAR1DRD4DRD2DPP7BACE1 | |
| SCHEMBL19614234 | 0.77 | DRD4 (0.70) | SIGMAR1DRD4DRD2DPP7BACE1 | |
| SCHEMBL17961749 | 0.77 | DRD4 (0.70) | SIGMAR1DRD4DRD2DPP7BACE1 | |
| SCHEMBL9851524 | 0.75 | GRM7 (0.59) | MTNR1AMTNR1BHRH3GRM7KMT2A | |
| SCHEMBL22399618 | 0.75 | FUCA1 (0.50) | SIGMAR1DRD4DRD2DPP7L3MBTL1 | |
| SCHEMBL5143427 | 0.75 | ALDH1A1 (0.60) | DRD4DRD2DPP7DRD3 | |
| SCHEMBL1623588 | 0.75 | ALDH1A1 (0.60) | DRD4DRD2DPP7DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002057257-A1 | CYCLO`C!AZEPANE DERIVATIVES WHICH ARE USED AS FARNESYLTRANSFERASE INHIBITORS AND METHOD FOR THE PREPARATION THEREFOR | LES LABORATOIRES SERVIER (FR) | 2002-07-25 | — | — | WO | disclosed |