Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24522302 | 0.88 | AKR1B1 (0.49) | MAOBAKR1B1HDAC4HDAC6GPR35 | |
| SCHEMBL30587208 | 0.86 | MAOB (0.45) | MAOBAKR1B1HDAC4HDAC6GPR35 | |
| SCHEMBL26113710 | 0.86 | MAOB (0.45) | MAOBAKR1B1HDAC4HDAC6GPR35 | |
| SCHEMBL27185752 | 0.83 | AKR1B1 (0.45) | MAOBAKR1B1HDAC4HDAC6GPR35 | |
| SCHEMBL19744184 | 0.80 | AKR1B1 (0.54) | MAOBAKR1B1GPR35TP53THRB | |
| SCHEMBL2303899 | 0.77 | MAOA (0.51) | MAOBHDAC4HDAC6KDM4EALDH1A1 | |
| SCHEMBL28373335 | 0.76 | MAOB (0.59) | MAOBAKR1B1HDAC4HDAC6KDM4E | |
| SCHEMBL28368123 | 0.75 | MAOB (0.57) | MAOBAKR1B1HDAC4HDAC6KDM4E | |
| SCHEMBL19744146 | 0.75 | GPR35 (0.60) | MAOBAKR1B1HDAC4HDAC6GPR35 | |
| SCHEMBL29540395 | 0.75 | GPR35 (0.60) | MAOBAKR1B1HDAC4HDAC6GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376491-B1 | BENZOFURAN DERIVATIVES FOR TREATMENT OR PREVENTION OF MYCOSIS IN MAMMALS | BASILEA PHARMACEUTICA AG (CH) | 2002-04-23 | — | — | US | disclosed |