Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699232 | 0.89 | ALDH1A1 (0.47) | TP53ALDH1A1KDM4EMAPTSIRT1 | |
| SCHEMBL7701056 | 0.88 | MAPT (0.47) | TP53ALDH1A1KDM4EMAPTSIRT1 | |
| SCHEMBL7695157 | 0.84 | IKBKB (0.48) | TP53ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL7698726 | 0.83 | LMNA (0.47) | MAPTPOLBIKBKBLMNA | |
| SCHEMBL7693804 | 0.82 | IKBKB (0.45) | TP53ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL7701939 | 0.81 | HSP90AA1 (0.47) | TP53ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL7693979 | 0.81 | IKBKB (0.42) | TP53ALDH1A1KDM4EMAPTSIRT1 | |
| SCHEMBL7697947 | 0.81 | KMT2A (0.47) | TP53ALDH1A1KDM4EMAPTTSHR | |
| SCHEMBL7697561 | 0.81 | POLB (0.54) | ALDH1A1KDM4ESIRT1TSHRPOLB | |
| SCHEMBL7699216 | 0.80 | IKBKB (0.41) | TP53ALDH1A1KDM4EMAPTSIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |