Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701056 | 0.87 | MAPT (0.47) | MAPTSMN1; SMN2KMT2AMEN1KDM4E | |
| SCHEMBL7699232 | 0.86 | ALDH1A1 (0.47) | MAPTHTTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7696235 | 0.84 | KMT2A (0.46) | MAPTLMNAHTTSMN1; SMN2KMT2A | |
| SCHEMBL7701939 | 0.84 | HSP90AA1 (0.47) | MAPTLMNAHTTSMN1; SMN2KMT2A | |
| SCHEMBL7699243 | 0.79 | TP53 (0.47) | MAPTLMNAHTTSMN1; SMN2TSHR | |
| SCHEMBL7695157 | 0.79 | IKBKB (0.48) | MAPTKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL7704549 | 0.79 | ALDH1A1 (0.39) | MAPTLMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7693910 | 0.78 | NPC1 (0.45) | HTTSMN1; SMN2KDM4EHSD17B10TRPV1 | |
| SCHEMBL7693979 | 0.78 | IKBKB (0.42) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL7697561 | 0.78 | POLB (0.54) | SMN1; SMN2KMT2AMEN1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |