Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701416 | 0.96 | F2 (0.50) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL7704678 | 0.94 | ALDH1A1 (0.53) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL7704003 | 0.89 | F2 (0.58) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7701431 | 0.88 | F2 (0.56) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| Dimethylamine SCHEMBL7699303 | 0.86 | RAB9A (0.51) | F2ALDH1A1RAB9AMAPTLMNA | |
| Dimethylamine SCHEMBL7701419 | 0.82 | RAB9A (0.51) | ALDH1A1RAB9ACA2CA12CA9 | |
| SCHEMBL13056579 | 0.81 | F2 (0.60) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL7699286 | 0.81 | ALDH1A1 (0.54) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL7701432 | 0.81 | ALDH1A1 (0.54) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| Dimethylamine SCHEMBL7704681 | 0.80 | RAB9A (0.57) | ALDH1A1RAB9AMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208109-A2 | NUCLEOSIDE ANALOGUES | NYCOMED AMERSHAM PLC (GB) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001016150-A2 | NUCLEOSIDE ANALOGUES | AMERSHAM PLC (GB) | 2001-03-08 | — | — | WO | disclosed |