Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL7699303 | 0.96 | RAB9A (0.51) | RAB9AALDH1A1NPSR1L3MBTL1HDAC1 | |
| Dimethylamine SCHEMBL7704681 | 0.94 | RAB9A (0.57) | RAB9AALDH1A1L3MBTL1HDAC1HDAC3 | |
| SCHEMBL7701416 | 0.86 | F2 (0.50) | RAB9AALDH1A1NPSR1L3MBTL1LMNA | |
| Dimethylamine SCHEMBL7704008 | 0.86 | ALDH1A1 (0.51) | ALDH1A1NPSR1HDAC1LMNAMAPT | |
| Dimethylamine SCHEMBL7704927 | 0.85 | RAB9A (0.48) | RAB9AALDH1A1NPSR1L3MBTL1HDAC1 | |
| Dimethylamine SCHEMBL7701434 | 0.85 | ALDH1A1 (0.50) | ALDH1A1NPSR1HDAC1LMNAMAPT | |
| SCHEMBL7699296 | 0.82 | F2 (0.50) | RAB9AALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL7704678 | 0.80 | ALDH1A1 (0.53) | RAB9AALDH1A1HDAC1HDAC3LMNA | |
| Dimethylamine SCHEMBL7699289 | 0.78 | ALDH1A1 (0.61) | RAB9AALDH1A1NPSR1L3MBTL1HDAC1 | |
| Dimethylamine SCHEMBL7701793 | 0.78 | ALDH1A1 (0.48) | ALDH1A1NPSR1HDAC1HDAC2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208109-A2 | NUCLEOSIDE ANALOGUES | NYCOMED AMERSHAM PLC (GB) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001016150-A2 | NUCLEOSIDE ANALOGUES | AMERSHAM PLC (GB) | 2001-03-08 | — | — | WO | disclosed |