Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699339 | 0.87 | PDGFRB (0.46) | PDGFRBPDGFRATHRBMAPK1LMNA | |
| SCHEMBL7692581 | 0.81 | PDGFRB (0.43) | MAPTTDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL7696498 | 0.79 | PDGFRB (0.55) | MEN1KMT2APDGFRBPDGFRA | |
| SCHEMBL7106618 | 0.75 | PDGFRB (0.53) | L3MBTL1PDGFRBPDGFRATHRBMAPK1 | |
| SCHEMBL7695428 | 0.74 | MAPKAPK2 (0.44) | MAPTMEN1KMT2APDGFRBPDGFRA | |
| SCHEMBL7695393 | 0.74 | PDGFRB (0.59) | MAPTMEN1KMT2APDGFRBPDGFRA | |
| SCHEMBL7699322 | 0.71 | PDGFRB (0.71) | MEN1KMT2APDGFRBPDGFRA | |
| SCHEMBL7691206 | 0.70 | KDM4E (0.43) | MAPTL3MBTL1MEN1KMT2APDGFRB | |
| SCHEMBL10439752 | 0.69 | ALDH1A1 (0.65) | MAPTTDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL7694543 | 0.69 | PDGFRB (0.52) | KMT2APDGFRBPDGFRARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |