Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8354280 | 0.70 | ADRA2A (0.47) | HDAC8HSP90AA1 | |
| SCHEMBL1854476 | 0.67 | — | — | |
| SCHEMBL1388023 | 0.67 | — | — | |
| SCHEMBL1854477 | 0.67 | — | — | |
| SCHEMBL29919450 | 0.65 | HDAC8 (0.39) | HDAC8HSP90AA1 | |
| SCHEMBL1352941 | 0.65 | HSP90AA1 (0.39) | HDAC8HSP90AA1 | |
| SCHEMBL2469365 | 0.65 | HDAC8 (0.39) | HDAC8HSP90AA1 | |
| SCHEMBL1029555 | 0.63 | — | — | |
| SCHEMBL4717596 | 0.62 | — | — | |
| SCHEMBL3050642 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9110840-A | — | — | None | — | — | JP | disclosed |
| JP-7017972-A | — | — | None | — | — | JP | disclosed |
| CN-1115339-C | Novel sulfonylaminopyrimidines | HOFFMANN LA ROCHE (CH) | 2003-07-23 | — | — | CN | disclosed |
| CN-1115339-C | Novel sulfonylaminopyrimidines | HOFFMANN LA ROCHE (CH) | 2003-07-23 | — | — | CN | disclosed |
| WO-2002083650-A1 | NOVEL SULFONYLAMINO-PYRIMIDINES | ACTELION PHARMACEUTICALS LTD (CH) | 2002-10-24 | — | — | WO | disclosed |
| WO-2002083650-A1 | NOVEL SULFONYLAMINO-PYRIMIDINES | ACTELION PHARMACEUTICALS LTD (CH) | 2002-10-24 | — | — | WO | disclosed |
| CN-1050839-C | Novel sulfonylamino pyrimidines | HOFFMANN LA ROCHE (CH) | 2000-03-29 | — | — | CN | disclosed |
| CN-1050839-C | Novel sulfonylamino pyrimidines | HOFFMANN LA ROCHE (CH) | 2000-03-29 | — | — | CN | disclosed |
| EP-0633259-B1 | Sulfonylaminopyrimidines, their preparation and their use as medicine | HOFFMANN LA ROCHE (CH) | 1999-01-13 | — | — | EP | disclosed |
| EP-0633259-B1 | Sulfonylaminopyrimidines, their preparation and their use as medicine | HOFFMANN LA ROCHE (CH) | 1999-01-13 | — | — | EP | disclosed |
| JP-H09110840-A | NEW SULFONYLAMINOPYRIMIDINES | F HOFFMANN LA ROCHE AG | 1997-04-28 | — | — | JP | disclosed |
| US-5541186-A | ENDOTHELIN RECEPTOR INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 1996-07-30 | — | — | US | disclosed |
| US-5541186-A | ENDOTHELIN RECEPTOR INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 1996-07-30 | — | — | US | disclosed |
| CN-1106007-A | Novel sulfonylamino pyrimidines | HOFFMANN LA ROCHE (CH) | 1995-08-02 | — | — | CN | disclosed |
| CN-1106007-A | Novel sulfonylamino pyrimidines | HOFFMANN LA ROCHE (CH) | 1995-08-02 | — | — | CN | disclosed |
| JP-H0717972-A | NOVEL SULFONYLAMINOPYRIMIDINE | F HOFFMANN LA ROCHE AG | 1995-01-20 | — | — | JP | disclosed |
| EP-0633259-A1 | Sulfonylaminopyrimidines, their preparation and their use as medicine | F. HOFFMANN-LA ROCHE AG (CH) | 1995-01-11 | — | — | EP | disclosed |
| EP-0633259-A1 | Sulfonylaminopyrimidines, their preparation and their use as medicine | F. HOFFMANN-LA ROCHE AG (CH) | 1995-01-11 | — | — | EP | disclosed |
| US-3716537-A | CERTAIN THENOYL DERIVATIVES OF BENZENSULFONYLAMINOPYRIMIDINES | BOEHRINGER MANNHEIM GMBH | 1973-02-13 | — | — | US | disclosed |
| US-3711564-A | NOVEL SULFONYLAMINOPYRIMIDINES AND COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH | 1973-01-16 | — | — | US | disclosed |