Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.69 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.69 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.69 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10387598 | 0.84 | SIGMAR1 (0.49) | SIGMAR1GRIN1GRIN2BACHEFUCA1 | |
| SCHEMBL1960380 | 0.76 | SIGMAR1 (0.71) | SIGMAR1GRIN1GRIN2BACHE | |
| SCHEMBL7697397 | 0.75 | SIGMAR1 (0.64) | SIGMAR1GRIN1GRIN2B | |
| SCHEMBL19779211 | 0.75 | SIGMAR1 (0.46) | SIGMAR1GRIN1GRIN2BACHETACR1 | |
| Hydrochloric Acid SCHEMBL8791549 | 0.75 | SIGMAR1 (0.68) | SIGMAR1GRIN1GRIN2BACHE | |
| SCHEMBL3604123 | 0.73 | SIGMAR1 (0.65) | SIGMAR1ACHETACR1FUCA1 | |
| SCHEMBL9307666 | 0.72 | SIGMAR1 (0.97) | SIGMAR1 | |
| SCHEMBL9308443 | 0.72 | SIGMAR1 (0.97) | SIGMAR1 | |
| SCHEMBL9308439 | 0.72 | SIGMAR1 (0.97) | SIGMAR1 | |
| SCHEMBL31134754 | 0.72 | ACHE (0.66) | SIGMAR1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002057258-A1 | CYCLO`D!AZEPANE DERIVATIVES WHICH ARE USED AS FARNESYLTRANSFERASE INHIBITORS AND METHOD FOR THE PREPARATION THEREOF | LES LABORATOIRES SERVIER (FR) | 2002-07-25 | — | — | WO | disclosed |