Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700382 | 0.89 | ALDH1A1 (0.37) | NPC1RAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL7701502 | 0.87 | HPGD (0.43) | NPC1RAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL7575384 | 0.86 | POLB (0.36) | NPC1RAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL7698367 | 0.85 | KDM4E (0.50) | NPC1RAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL7699527 | 0.85 | KDM4E (0.50) | NPC1RAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL7520327 | 0.83 | PTPN1 (0.43) | NPC1RAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL7582515 | 0.83 | HPGD (0.37) | NPC1RAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL7580060 | 0.79 | HDAC1 (0.38) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7564276 | 0.76 | CYP1A2 (0.39) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL5844070 | 0.76 | HPGD (0.39) | NPC1RAB9AALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002004458-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPASES) | NOVO NORDISK A/S (DK) | 2002-01-17 | — | — | WO | claimed |
| WO-2002004458-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPASES) | NOVO NORDISK A/S (DK) | 2002-01-17 | — | — | WO | disclosed |