Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | HPGD | P15428 | 4/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | TARBP2 | Q15633 | 7/20 | 0.65 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29158580 | 1.00 | ALDH1A1 (0.69) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL7698049 | 0.91 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL27189076 | 0.90 | TARBP2 (0.78) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL4499055 | 0.90 | TARBP2 (0.73) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL7699330 | 0.88 | KDM4E (0.53) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL7693955 | 0.87 | KDM4E (0.52) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL7701292 | 0.86 | TARBP2 (0.67) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL7699490 | 0.85 | TARBP2 (0.67) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL16005699 | 0.85 | TARBP2 (0.72) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL29158677 | 0.85 | TARBP2 (0.72) | ALDH1A1KDM4EHPGDHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |