Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 13/20 | 0.41 |
| ▸ | MMP9 | P14780 | 11/20 | 0.41 |
| ▸ | MMP1 | P03956 | 11/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7511398 | 0.95 | MMP13 (0.45) | MMP13MMP9MMP1MMP2MMP8 | |
| SCHEMBL7510529 | 0.92 | MMP13 (0.51) | MMP13MMP9MMP1MMP2MMP8 | |
| SCHEMBL7510025 | 0.92 | MMP13 (0.39) | MMP13MMP9MMP1MMP2MMP8 | |
| SCHEMBL7643961 | 0.88 | MMP13 (0.42) | MMP13MMP9MMP1MMP2MMP8 | |
| SCHEMBL8000935 | 0.84 | MMP13 (0.43) | MMP13MMP9MMP1MMP2MMP8 | |
| SCHEMBL7641613 | 0.83 | MMP13 (0.56) | MMP13MMP9MMP1ADAM17 | |
| Hydrochloric Acid SCHEMBL7628507 | 0.82 | MMP1 (0.61) | MMP13MMP9MMP1ADAM17 | |
| SCHEMBL7348654 | 0.80 | MMP9 (0.43) | MMP13MMP9MMP1ADAM17LMNA | |
| SCHEMBL7516482 | 0.79 | MMP13 (0.46) | MMP13MMP9MMP1MMP2MMP8 | |
| SCHEMBL7557038 | 0.77 | MMP13 (0.44) | MMP13MMP9MMP1ADAM17SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342508-B1 | ENZYME INHIBITORS FOR PROTECTION OF CONNECTIVE TISSUES | AMERICAN CYANAMID COMPANY | 2002-01-29 | — | — | US | disclosed |