Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | LRRK2 | Q5S007 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | CDK1 | P06493 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701083 | 0.89 | LRRK2 (0.52) | DYRK1ALRRK2KDM4ETSHRMAPK1 | |
| SCHEMBL8991102 | 0.85 | DYRK1A (0.56) | DYRK1ALRRK2KDM4ETSHRMAPK1 | |
| SCHEMBL7696582 | 0.83 | DYRK1A (0.57) | DYRK1ALRRK2KDM4ETSHRMAPK1 | |
| SCHEMBL7698534 | 0.82 | DYRK1A (0.60) | DYRK1ALRRK2ADORA2AADORA1HSPA8 | |
| SCHEMBL7701581 | 0.81 | DYRK1A (0.55) | DYRK1ALRRK2KDM4ETSHRMAPK1 | |
| SCHEMBL7703241 | 0.80 | DYRK1A (0.56) | DYRK1ALRRK2KDM4EPIK3CDHSPA8 | |
| SCHEMBL8991180 | 0.76 | LRRK2 (0.43) | LRRK2KDM4ETSHRMAPK1HTT | |
| SCHEMBL7699825 | 0.76 | DYRK1A (0.51) | DYRK1ALRRK2KDM4ETSHRMAPK1 | |
| SCHEMBL7695781 | 0.75 | DYRK1A (0.56) | DYRK1ALRRK2KDM4ETSHRMAPK1 | |
| SCHEMBL7696326 | 0.75 | LRRK2 (0.44) | LRRK2KDM4ETSHRMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |