Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.55 |
| ▸ | LRRK2 | Q5S007 | 8/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696582 | 0.93 | DYRK1A (0.57) | DYRK1ALRRK2ADORA2AADORA1KDM4E | |
| SCHEMBL7698547 | 0.88 | LRRK2 (0.56) | DYRK1ALRRK2ADORA2AADORA1KDM4E | |
| SCHEMBL8991102 | 0.86 | DYRK1A (0.56) | DYRK1ALRRK2ADORA2AADORA1KDM4E | |
| SCHEMBL7701231 | 0.82 | DYRK1A (0.55) | DYRK1ALRRK2ADORA2AADORA1KDM4E | |
| SCHEMBL7699564 | 0.81 | DYRK1A (0.51) | DYRK1ALRRK2ADORA2AADORA1KDM4E | |
| SCHEMBL7701233 | 0.81 | DYRK1A (0.51) | DYRK1ALRRK2ADORA2AADORA1KDM4E | |
| SCHEMBL7700915 | 0.78 | DYRK1A (0.50) | DYRK1ALRRK2ADORA2AADORA1PIK3CD | |
| SCHEMBL7703717 | 0.77 | MEN1 (0.48) | DYRK1ALRRK2ADORA2AADORA1KDM4E | |
| SCHEMBL7699825 | 0.76 | DYRK1A (0.51) | DYRK1ALRRK2ADORA2AADORA1KDM4E | |
| SCHEMBL7695781 | 0.76 | DYRK1A (0.56) | DYRK1ALRRK2ADORA2AADORA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |