Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.56 |
| ▸ | LRRK2 | Q5S007 | 10/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | PIK3R2 | O00459 | 2/20 | 0.35 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701687 | 0.88 | LRRK2 (0.54) | DYRK1ALRRK2CDK5CDK5R1PIK3CD | |
| SCHEMBL7698534 | 0.87 | DYRK1A (0.60) | DYRK1ALRRK2CDK5CDK5R1HSPA8 | |
| SCHEMBL7699564 | 0.80 | DYRK1A (0.51) | DYRK1ALRRK2PIK3CDHSPA8RET | |
| SCHEMBL8991164 | 0.76 | LRRK2 (0.40) | DYRK1ALRRK2CDK5CDK5R1PIK3CD | |
| SCHEMBL7699827 | 0.75 | DYRK1A (0.54) | DYRK1ALRRK2PIK3CDKDM4EALDH1A1 | |
| SCHEMBL7695781 | 0.75 | DYRK1A (0.56) | DYRK1ALRRK2CDK5CDK5R1PIK3CD | |
| SCHEMBL7697510 | 0.74 | LRRK2 (0.58) | DYRK1ALRRK2CDK5CDK5R1PIK3CD | |
| SCHEMBL7703364 | 0.74 | DYRK1A (0.59) | DYRK1ALRRK2CDK5CDK5R1PIK3CD | |
| SCHEMBL7701195 | 0.74 | ADK (0.42) | DYRK1ALRRK2PIK3CDJAK2JAK1 | |
| SCHEMBL7702669 | 0.73 | DYRK1A (0.57) | DYRK1ALRRK2PIK3CDKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |