Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | AS3MT | Q9HBK9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701083 | 0.87 | LRRK2 (0.52) | LRRK2EGFRERBB2ADORA2ASRC | |
| SCHEMBL8991158 | 0.85 | KMT2A (0.49) | LRRK2EGFRERBB2ADORA2AKMT2A | |
| SCHEMBL8991084 | 0.84 | LRRK2 (0.42) | LRRK2EGFRSRCKDM4EHSD17B10 | |
| SCHEMBL8991164 | 0.81 | LRRK2 (0.40) | LRRK2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL8991214 | 0.80 | EGFR (0.38) | EGFRERBB2ADORA2ASRCHSPA5 | |
| SCHEMBL8991354 | 0.80 | EGFR (0.38) | EGFRERBB2ADORA2ASRCHSPA5 | |
| SCHEMBL8991228 | 0.78 | PDE4A (0.37) | EGFRERBB2ADORA2ASRCHSPA5 | |
| SCHEMBL8991276 | 0.77 | MEN1 (0.40) | LRRK2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL8991348 | 0.76 | ALDH1A1 (0.44) | LRRK2EGFRSRCKMT2AMEN1 | |
| SCHEMBL7699564 | 0.76 | DYRK1A (0.51) | LRRK2EGFRERBB2ADORA2ASRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |