Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | EZH2 | Q15910 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7707671 | 0.78 | POLB (0.47) | POLBEZH2HTTKMT2AKDM4E | |
| SCHEMBL8779022 | 0.78 | POLB (0.47) | POLBEZH2HTTKMT2AKDM4E | |
| SCHEMBL7699677 | 0.77 | EZH2 (0.60) | POLBEZH2HTTKMT2AKDM4E | |
| SCHEMBL10525359 | 0.73 | POLB (0.59) | POLBEZH2HTTKMT2AKDM4E | |
| SCHEMBL2289255 | 0.72 | GAA (0.62) | POLBEZH2HTTKMT2AKDM4E | |
| SCHEMBL8738156 | 0.69 | EZH2 (0.76) | POLBEZH2KMT2AMEN1L3MBTL1 | |
| SCHEMBL19414235 | 0.69 | GAA (0.54) | POLBEZH2HTTKMT2AKDM4E | |
| SCHEMBL10690004 | 0.68 | RECQL (0.47) | POLBEZH2HTTKMT2AKDM4E | |
| SCHEMBL8029766 | 0.68 | RECQL (0.47) | POLBEZH2HTTKMT2AKDM4E | |
| SCHEMBL11317525 | 0.68 | LMNA (0.67) | POLBEZH2HTTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6353044-B1 | PHOTOSTABILITY OF POLYMER WITH BETA-(2,2,6,6-TETRAMETHYL PIPERIDINE-4-AMINO)ETHYL CROTONATE | GREAT LAKES CHEMICAL ITALIA S.R.L. (IT) | 2002-03-05 | — | — | US | claimed |
| EP-0975626-A1 | ENAMINE DERIVATIVES FOR USE AS ANTIOXYDANTS FOR POLYMERS | Great Lakes Chemical (Europe) GmbH (CH) | 2000-02-02 | — | — | EP | claimed |
| WO-1998047893-A1 | ENAMINE DERIVATIVES FOR USE AS ANTIOXYDANTS FOR POLYMERS | GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) | 1998-10-29 | — | — | WO | claimed |
| US-6353044-B1 | PHOTOSTABILITY OF POLYMER WITH BETA-(2,2,6,6-TETRAMETHYL PIPERIDINE-4-AMINO)ETHYL CROTONATE | GREAT LAKES CHEMICAL ITALIA S.R.L. (IT) | 2002-03-05 | — | — | US | disclosed |
| EP-0983240-A1 | LIGHT-STABILIZED ORGANIC POLYMERS | Great Lakes Chemical (Europe) GmbH (CH) | 2000-03-08 | — | — | EP | disclosed |
| EP-0975626-A1 | ENAMINE DERIVATIVES FOR USE AS ANTIOXYDANTS FOR POLYMERS | Great Lakes Chemical (Europe) GmbH (CH) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998050360-A1 | LIGHT-STABILIZED ORGANIC POLYMERS | GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) | 1998-11-12 | — | — | WO | disclosed |
| WO-1998047893-A1 | ENAMINE DERIVATIVES FOR USE AS ANTIOXYDANTS FOR POLYMERS | GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) | 1998-10-29 | — | — | WO | disclosed |