Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 6/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7705142 | 0.86 | EZH2 (0.60) | EZH2POLBHTTKMT2AKDM4E | |
| SCHEMBL2908330 | 0.80 | EZH2 (0.89) | EZH2POLBKMT2AMEN1L3MBTL1 | |
| SCHEMBL8779022 | 0.79 | POLB (0.47) | EZH2POLBHTTKMT2AKDM4E | |
| SCHEMBL7707671 | 0.79 | POLB (0.47) | EZH2POLBHTTKMT2AKDM4E | |
| SCHEMBL8029766 | 0.78 | RECQL (0.47) | EZH2POLBHTTKMT2AKDM4E | |
| SCHEMBL10690004 | 0.78 | RECQL (0.47) | EZH2POLBHTTKMT2AKDM4E | |
| SCHEMBL3066205 | 0.77 | RAB9A (0.52) | HTTKMT2AMEN1TSHRGAA | |
| SCHEMBL3066206 | 0.77 | RAB9A (0.52) | HTTKMT2AMEN1TSHRGAA | |
| SCHEMBL7699689 | 0.77 | POLB (0.44) | EZH2POLBHTTKMT2AKDM4E | |
| SCHEMBL8738588 | 0.75 | EZH2 (1.00) | EZH2POLBKMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6353044-B1 | PHOTOSTABILITY OF POLYMER WITH BETA-(2,2,6,6-TETRAMETHYL PIPERIDINE-4-AMINO)ETHYL CROTONATE | GREAT LAKES CHEMICAL ITALIA S.R.L. (IT) | 2002-03-05 | — | — | US | claimed |
| US-6353044-B1 | PHOTOSTABILITY OF POLYMER WITH BETA-(2,2,6,6-TETRAMETHYL PIPERIDINE-4-AMINO)ETHYL CROTONATE | GREAT LAKES CHEMICAL ITALIA S.R.L. (IT) | 2002-03-05 | — | — | US | disclosed |