Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | EZH2 | Q15910 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7707671 | 1.00 | POLB (0.47) | POLBRECQLEZH2HTTGAA | |
| SCHEMBL8029766 | 0.88 | RECQL (0.47) | POLBRECQLEZH2HTTGAA | |
| SCHEMBL10690004 | 0.88 | RECQL (0.47) | POLBRECQLEZH2HTTGAA | |
| SCHEMBL7699677 | 0.79 | EZH2 (0.60) | POLBEZH2HTTGAAKDM4E | |
| SCHEMBL8029546 | 0.79 | MEN1 (0.46) | POLBRECQLHTTGAAKDM4E | |
| SCHEMBL7699689 | 0.78 | POLB (0.44) | POLBEZH2HTTGAAKDM4E | |
| SCHEMBL28402532 | 0.77 | POLB (0.57) | POLBRECQLEZH2HTTGAA | |
| SCHEMBL77511 | 0.77 | RECQL (0.55) | POLBRECQLEZH2HTTGAA | |
| SCHEMBL26680180 | 0.76 | POLB (0.56) | POLBRECQLEZH2HTTGAA | |
| SCHEMBL3050149 | 0.76 | POLB (0.56) | POLBRECQLEZH2HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517658-B1 | Stabilisation of polymeric organic materials by using synergistic mixtures comprising sterically hindered cyclic amines and derivatives of 3-pyrazolidinone or 1,2,4-triazolidine-3,5-dione | CIBA GEIGY AG (CH) | 1997-01-29 | — | — | EP | disclosed |
| US-5457143-A | Light, heat and oxydiation resistance | CIBA-GEIGY CORPORATION (US) | 1995-10-10 | — | — | US | disclosed |
| EP-0517658-A1 | Stabilisation of polymeric organic materials by using synergistic mixtures comprising sterically hindered cyclic amines and derivatives of 3-pyrazolidinone or 1,2,4-triazolidine-3,5-dione | CIBA-GEIGY AG (CH) | 1992-12-09 | — | — | EP | disclosed |