Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | UBE2N | P61088 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700596 | 0.91 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL7699365 | 0.87 | L3MBTL1 (0.75) | L3MBTL1ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL7701108 | 0.85 | KMT2A (0.62) | L3MBTL1ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL7700945 | 0.84 | ALDH1A1 (0.60) | L3MBTL1ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL7694777 | 0.84 | MAPT (0.58) | L3MBTL1ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL7698770 | 0.82 | MAPT (0.61) | ALDH1A1MAPTKDM4EHTTGAA | |
| SCHEMBL7696680 | 0.81 | MAPT (0.62) | ALDH1A1MAPTHPGDKDM4EGAA | |
| SCHEMBL7696767 | 0.81 | ALDH1A1 (0.55) | L3MBTL1ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL7701848 | 0.80 | KMT2A (0.66) | L3MBTL1ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL7700470 | 0.80 | KMT2A (0.44) | L3MBTL1ALDH1A1MAPTHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |