Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 5/20 | 0.41 |
| ▸ | FYN | P06241 | 4/20 | 0.41 |
| ▸ | VCP | P55072 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | YES1 | P07947 | 2/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.40 |
| ▸ | RET | P07949 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | PLK4 | O00444 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991371 | 0.88 | MAPK1 (0.44) | KDM4EMAPK1HTTTSHRHSD17B10 | |
| SCHEMBL8991048 | 0.88 | KDM4E (0.57) | KDM4EMAPK1HTTTSHRHSD17B10 | |
| SCHEMBL8991267 | 0.87 | KDM4E (0.48) | KDM4EMAPK1HTTTSHRHSD17B10 | |
| SCHEMBL8991286 | 0.87 | GAA (0.41) | KDM4EMAPK1HTTTSHRHSD17B10 | |
| SCHEMBL8991144 | 0.86 | KDM4E (0.48) | KDM4EMAPK1HTTTSHRHSD17B10 | |
| SCHEMBL8991123 | 0.81 | KDM4E (0.44) | KDM4EMAPK1HTTTSHRHSD17B10 | |
| SCHEMBL7701563 | 0.79 | KDM4E (0.47) | KDM4EMAPK1HTTTSHRHSD17B10 | |
| SCHEMBL8991261 | 0.78 | KDM4E (0.49) | KDM4EMAPK1HTTTSHRHSD17B10 | |
| SCHEMBL8991414 | 0.78 | KDM4E (0.57) | KDM4EMAPK1HTTTSHRHSD17B10 | |
| SCHEMBL8991169 | 0.77 | MAPK1 (0.45) | KDM4EMAPK1HTTTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |