Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | CTSE | P14091 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MRGPRX2 | Q96LB1 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8656342 | 1.00 | SLC6A4 (0.58) | SLC6A4SLC6A2SLC6A3OPRM1OPRD1 | |
| SCHEMBL11391861 | 1.00 | SLC6A4 (0.58) | SLC6A4SLC6A2SLC6A3OPRM1OPRD1 | |
| SCHEMBL8434553 | 1.00 | SLC6A4 (0.58) | SLC6A4SLC6A2SLC6A3OPRM1OPRD1 | |
| Ethylene SCHEMBL11397601 | 0.98 | OPRM1 (0.56) | SLC6A4SLC6A2SLC6A3OPRM1OPRD1 | |
| SCHEMBL8396855 | 0.87 | OPRD1 (0.76) | SLC6A4SLC6A2SLC6A3OPRM1OPRD1 | |
| SCHEMBL11398571 | 0.87 | OPRD1 (0.76) | SLC6A4SLC6A2SLC6A3OPRM1OPRD1 | |
| SCHEMBL8396856 | 0.87 | OPRD1 (0.76) | SLC6A4SLC6A2SLC6A3OPRM1OPRD1 | |
| SCHEMBL7486453 | 0.86 | OPRM1 (0.60) | SLC6A4SLC6A2SLC6A3OPRM1OPRD1 | |
| SCHEMBL11403981 | 0.86 | OPRD1 (0.55) | SLC6A4SLC6A2SLC6A3OPRM1OPRD1 | |
| SCHEMBL7486456 | 0.86 | OPRM1 (0.60) | SLC6A4SLC6A2SLC6A3OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6337330-B1 | Antitussives | TORAY INDUSTRIES, INC. (JP) | 2002-01-08 | — | — | US | disclosed |
| EP-0998928-A1 | ANTITUSSIVES | TORAY INDUSTRIES, INC. (JP) | 2000-05-10 | — | — | EP | disclosed |