Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.48 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.40 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700195 | 1.00 | PRCP (0.48) | PRCPKDM1ACYP2D6RECQLPARP10 | |
| SCHEMBL7703323 | 0.83 | TRPM5 (0.57) | PRCPKDM1ARECQLPARP10TRPM5 | |
| SCHEMBL7703317 | 0.83 | TRPM5 (0.57) | PRCPKDM1ARECQLPARP10TRPM5 | |
| SCHEMBL7703320 | 0.83 | TRPM5 (0.57) | PRCPKDM1ARECQLPARP10TRPM5 | |
| SCHEMBL7702387 | 0.82 | RECQL (0.59) | PRCPRECQLMAPTMEN1KMT2A | |
| SCHEMBL5023257 | 0.82 | RECQL (0.59) | PRCPRECQLMAPTMEN1KMT2A | |
| SCHEMBL7698338 | 0.82 | RECQL (0.59) | PRCPRECQLMAPTMEN1KMT2A | |
| SCHEMBL2364359 | 0.78 | PRCP (0.67) | PRCPKDM1ARECQLTRPM5MEN1 | |
| SCHEMBL30973233 | 0.78 | PRCP (0.67) | PRCPKDM1ARECQLTRPM5MEN1 | |
| SCHEMBL13736863 | 0.74 | TRPM5 (0.35) | PRCPRECQLTRPM5NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901488-B1 | 2,4-DIAMINOPYRIMIDINE DERIVATIVES | BASILEA PHARMACEUTICA AG (CH) | 2002-11-06 | — | — | EP | disclosed |
| US-5866583-A | Substituted 2,4-diaminopyrimidines | HOFFMANN-LA ROCHE INC. (US) | 1999-02-02 | — | — | US | disclosed |