SCHEMBL770026

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL769874	0.81	MAPT (0.51)	HTTGAAALOX12LMNAALDH1A1
	SCHEMBL770107	0.79	MAPT (0.50)	HTTLMNAALDH1A1MAPTHPGD
	SCHEMBL770037	0.77	KMT2A (0.51)	CNR2CNR1ALOX12LMNAALDH1A1
	SCHEMBL15201290	0.74	FGFR1 (0.59)	HTTGAALMNAALDH1A1MAPT
	SCHEMBL769873	0.72	MAPT (0.54)	HTTGAAALOX12LMNAALDH1A1
	SCHEMBL769872	0.72	MAPT (0.56)	HTTGAAALOX12LMNAALDH1A1
	SCHEMBL769761	0.71	NPC1 (0.64)	HTTGAAALOX12LMNAALDH1A1
	SCHEMBL15064400	0.71	CNR2 (1.00)	CNR2CNR1LMNAALDH1A1NPSR1
	SCHEMBL15064731	0.71	CNR2 (1.00)	CNR2CNR1
	SCHEMBL15201869	0.69	ALDH1A1 (0.57)	HTTGAAALOX12LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.