Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694358 | 0.90 | RXFP1 (0.41) | TP53MAPTHDAC1PDE4BPDE11A | |
| SCHEMBL7699810 | 0.86 | EPHX2 (0.45) | — | |
| SCHEMBL7698091 | 0.84 | HTT (0.46) | TP53HTTMAPTPDE4BPDE11A | |
| SCHEMBL7701315 | 0.83 | MTNR1A (0.45) | TP53MAPTALDH1A1HPGDKDM4E | |
| SCHEMBL7700063 | 0.83 | KDM4E (0.52) | TP53HTTMAPTALDH1A1HPGD | |
| SCHEMBL7693765 | 0.81 | EPHX2 (0.44) | TP53HTTMAPTALDH1A1HPGD | |
| SCHEMBL7700011 | 0.80 | HTT (0.53) | TP53HTTMAPTALDH1A1HPGD | |
| SCHEMBL7698708 | 0.78 | CNR1 (0.49) | — | |
| SCHEMBL7695359 | 0.77 | EPHX2 (0.44) | TP53MAPTALDH1A1HPGDKDM4E | |
| SCHEMBL7699576 | 0.76 | KDM4E (0.48) | TP53HTTMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |