Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | IKBKB | O14920 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7693765 | 0.91 | EPHX2 (0.44) | RXFP1IKBKBROCK2MAPTPOLB | |
| SCHEMBL7700263 | 0.90 | TP53 (0.47) | MAPTPOLBTP53HPGDKDM4E | |
| SCHEMBL7699810 | 0.79 | EPHX2 (0.45) | IKBKBROCK2 | |
| SCHEMBL7695824 | 0.79 | ALDH1A1 (0.45) | RXFP1MAPTTP53HPGDKDM4E | |
| SCHEMBL7693745 | 0.77 | IKBKB (0.53) | RXFP1IKBKBMAPTTP53HPGD | |
| SCHEMBL7701315 | 0.77 | MTNR1A (0.45) | RXFP1IKBKBMAPTTP53HPGD | |
| SCHEMBL7698091 | 0.76 | HTT (0.46) | MAPTPOLBTP53HPGDKDM4E | |
| SCHEMBL7694392 | 0.76 | TARBP2 (0.51) | RXFP1IKBKBMAPTTP53HPGD | |
| SCHEMBL7699576 | 0.75 | KDM4E (0.48) | RXFP1IKBKBMAPTPOLBTP53 | |
| SCHEMBL7700875 | 0.75 | MEN1 (0.56) | MAPTPOLBTP53KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |