Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700942 | 0.87 | EPHX2 (0.44) | KDM4ELMNA | |
| SCHEMBL7698726 | 0.86 | LMNA (0.47) | POLBMAPTLMNA | |
| SCHEMBL7700011 | 0.85 | HTT (0.53) | HTTTP53POLBGAAKDM4E | |
| SCHEMBL7699627 | 0.85 | IKBKB (0.40) | HTTTP53POLBKDM4ENPC1 | |
| SCHEMBL7700263 | 0.84 | TP53 (0.47) | HTTTP53POLBGAAKDM4E | |
| SCHEMBL7693979 | 0.83 | IKBKB (0.42) | TP53POLBKDM4EALDH1A1MAPT | |
| SCHEMBL7695326 | 0.81 | IKBKB (0.40) | TP53GAAKDM4ENPC1ALDH1A1 | |
| SCHEMBL7700674 | 0.81 | RAB9A (0.42) | TP53POLBKDM4EALDH1A1MAPT | |
| SCHEMBL7699232 | 0.80 | ALDH1A1 (0.47) | HTTTP53GAAKDM4ENPC1 | |
| SCHEMBL7701939 | 0.80 | HSP90AA1 (0.47) | HTTTP53GAAKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |