Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 4/20 | 0.39 |
| ▸ | SRC | P12931 | 3/20 | 0.39 |
| ▸ | ABL1 | P00519 | 3/20 | 0.39 |
| ▸ | ABL2 | P42684 | 3/20 | 0.39 |
| ▸ | CDK1 | P06493 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | RET | P07949 | 5/20 | 0.38 |
| ▸ | AHCY | P23526 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991228 | 0.88 | PDE4A (0.37) | KDM4ETSHRMAPK1HTTHSD17B10 | |
| SCHEMBL8991429 | 0.85 | MAPK1 (0.54) | KDM4ETSHRMAPK1HTTHSD17B10 | |
| SCHEMBL7701709 | 0.83 | RET (0.36) | KDM4ETSHRMAPK1HTTHSD17B10 | |
| SCHEMBL8990968 | 0.82 | KDM4E (0.42) | KDM4ETSHRMAPK1HTTHSD17B10 | |
| SCHEMBL7703321 | 0.81 | RET (0.38) | RET | |
| SCHEMBL8990961 | 0.79 | KDM4E (0.44) | KDM4ETSHRMAPK1HTTHSD17B10 | |
| SCHEMBL7700288 | 0.79 | KDM4E (0.44) | KDM4ETSHRMAPK1HTTHSD17B10 | |
| SCHEMBL7699500 | 0.79 | IGF1R (0.42) | KDM4ETSHRMAPK1HTTHSD17B10 | |
| SCHEMBL8991108 | 0.77 | KDM4E (0.46) | KDM4ETSHRMAPK1HTTHSD17B10 | |
| SCHEMBL7701083 | 0.76 | LRRK2 (0.52) | KDM4ETSHRMAPK1HTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |