Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 2/20 | 0.39 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 4/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | ATG7 | O95352 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991238 | 0.89 | AURKA (0.40) | KDM4ETSHRMAPK1HTTHSD17B10 | |
| SCHEMBL8991429 | 0.88 | MAPK1 (0.54) | KDM4ETSHRMAPK1HTTHSD17B10 | |
| SCHEMBL8991162 | 0.83 | KDM4E (0.46) | KDM4ETSHRMAPK1HTTHSD17B10 | |
| SCHEMBL8991491 | 0.82 | HTT (0.42) | KDM4ETSHRMAPK1HTTHSD17B10 | |
| SCHEMBL8991022 | 0.81 | KDM4E (0.44) | KDM4ETSHRMAPK1HTTHSD17B10 | |
| SCHEMBL8991185 | 0.81 | KDM4E (0.41) | KDM4ETSHRMAPK1HTTHSD17B10 | |
| SCHEMBL8991144 | 0.81 | KDM4E (0.48) | KDM4ETSHRMAPK1HTTHSD17B10 | |
| SCHEMBL8991099 | 0.81 | KDM4E (0.48) | KDM4ETSHRMAPK1HTTHSD17B10 | |
| SCHEMBL7697687 | 0.80 | RIPK1 (0.42) | KDM4ETSHRMAPK1HTTHSD17B10 | |
| SCHEMBL8990972 | 0.77 | MEN1 (0.46) | KDM4ETSHRMAPK1HTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |