Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 16/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991298 | 0.88 | RET (0.33) | RETENPP1 | |
| SCHEMBL7701709 | 0.87 | RET (0.36) | RETRPS6KA3 | |
| SCHEMBL7700291 | 0.81 | KDM4E (0.41) | RET | |
| SCHEMBL8991126 | 0.80 | RET (0.36) | RETENPP1RPS6KA3 | |
| SCHEMBL7703318 | 0.78 | RET (0.39) | RET | |
| SCHEMBL8991118 | 0.78 | RET (0.38) | RETENPP1 | |
| SCHEMBL7700384 | 0.78 | ENPP1 (0.39) | RETENPP1NT5E | |
| SCHEMBL8991022 | 0.76 | KDM4E (0.44) | RET | |
| SCHEMBL8991012 | 0.76 | XDH (0.33) | RET | |
| SCHEMBL7701687 | 0.74 | LRRK2 (0.54) | RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |