Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 4/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700291 | 0.88 | KDM4E (0.41) | EGFRSRCKDM4ETSHRMAPK1 | |
| SCHEMBL8990972 | 0.87 | MEN1 (0.46) | PDE4APDE4BPDE4CPDE4DEGFR | |
| SCHEMBL8991012 | 0.86 | XDH (0.33) | RET | |
| SCHEMBL8991298 | 0.83 | RET (0.33) | RET | |
| SCHEMBL8991354 | 0.81 | EGFR (0.38) | PDE4APDE4BPDE4CPDE4DEGFR | |
| SCHEMBL8991214 | 0.81 | EGFR (0.38) | PDE4APDE4BPDE4CPDE4DEGFR | |
| SCHEMBL8991378 | 0.80 | ADORA2A (0.41) | PDE4APDE4BPDE4CPDE4DEGFR | |
| SCHEMBL8991238 | 0.79 | AURKA (0.40) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL8991129 | 0.78 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DEGFR | |
| SCHEMBL8991147 | 0.78 | GAA (0.39) | PDE4APDE4BPDE4CPDE4DMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |