Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PRCP | P42785 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24946122 | 0.81 | SLC6A4 (0.57) | LMNATSHRSLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL6203736 | 0.79 | SLC6A4 (0.55) | LMNATSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21916840 | 0.78 | SLC6A4 (0.58) | LMNATSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29101204 | 0.75 | OPRM1 (0.53) | LMNATSHRSLC6A2SLC6A4SLC6A3 | |
| Tiletamine SCHEMBL115212 | 0.75 | LMNA (1.00) | LMNATSHRSLC6A2SLC6A4SLC6A3 | |
| Tiletamine SCHEMBL258460 | 0.74 | LMNA (0.97) | LMNATSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17835223 | 0.74 | SLC6A2 (0.69) | LMNATSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL353542 | 0.73 | HDAC3 (0.42) | LMNATSHRSLC6A2SLC6A4SLC6A3 | |
| Eticyclidine SCHEMBL66697 | 0.72 | GRIN2D (0.57) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9640387 | 0.71 | HDAC3 (0.51) | LMNATSHRSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986555-A1 | NOVEL PHENCYCLIDINE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2000-03-22 | — | — | EP | claimed |
| WO-1998055478-A1 | NOVEL PHENCYCLIDINE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1998-12-10 | — | — | WO | claimed |
| US-6342511-B1 | RACEMIC, ENANTIOMORPHS AND DIASTERIOMORPHS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2002-01-29 | — | — | US | disclosed |