Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PRCP | P42785 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9641290 | 0.76 | LMNA (0.52) | HDAC3HDAC1HDAC2HDAC6SLC6A4 | |
| SCHEMBL24946122 | 0.75 | SLC6A4 (0.57) | HDAC3HDAC1HDAC2HDAC6SLC6A2 | |
| SCHEMBL7695144 | 0.75 | HDAC3 (0.48) | HDAC3HDAC1HDAC2HDAC6SLC6A2 | |
| SCHEMBL9641234 | 0.74 | HDAC3 (0.42) | HDAC3HDAC1HDAC2HDAC6SLC6A2 | |
| SCHEMBL28849376 | 0.73 | SSTR4 (0.56) | HDAC3HDAC1HDAC2HDAC6 | |
| Hydrochloric Acid SCHEMBL6203736 | 0.73 | SLC6A4 (0.55) | HDAC3HDAC1HDAC2HDAC6SLC6A2 | |
| SCHEMBL21916840 | 0.72 | SLC6A4 (0.58) | HDAC3HDAC1HDAC2HDAC6SLC6A2 | |
| SCHEMBL9640296 | 0.72 | RAB9A (0.56) | MEN1KMT2ACTSDBACE1LMNA | |
| SCHEMBL28826580 | 0.72 | HDAC3 (0.45) | HDAC3HDAC1HDAC2HDAC6SLC6A4 | |
| SCHEMBL9640292 | 0.71 | SSTR4 (0.54) | HDAC3HDAC1HDAC2HDAC6POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293880-B1 | ANTIHYPERLIPIDEMIC AND ANTIATHEROSCLEROTIC UREA COMPOUNDS | WARNER-LAMBERT COMPANY (US) | 1992-08-26 | — | — | EP | claimed |
| EP-0293880-A1 | Antihyperlipidemic and antiatherosclerotic urea compounds | WARNER-LAMBERT COMPANY (US) | 1988-12-07 | — | — | EP | claimed |
| EP-0293880-B1 | ANTIHYPERLIPIDEMIC AND ANTIATHEROSCLEROTIC UREA COMPOUNDS | WARNER-LAMBERT COMPANY (US) | 1992-08-26 | — | — | EP | disclosed |
| EP-0293880-A1 | Antihyperlipidemic and antiatherosclerotic urea compounds | WARNER-LAMBERT COMPANY (US) | 1988-12-07 | — | — | EP | disclosed |