SCHEMBL7700314

SCHEMBL7700314

O=C(CC(=O)C1CCCCC1)OCc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.51
MAPK1 P28482 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
EPHX1 P07099 1/20 0.50
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
CYP2C19 P33261 2/20 0.49
GAA P10253 1/20 0.49
TSHR P16473 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
ENPP2 Q13822 1/20 0.45
USP2 O75604 1/20 0.45
HPGD P15428 1/20 0.45
EPHX2 P34913 1/20 0.45
SGMS2 Q8NHU3 1/20 0.45
ALOX12 P18054 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8194806 0.98 ALDH1A1 (0.53) ALDH1A1MAPK1L3MBTL1EPHX1MEN1
SCHEMBL7689034 0.95 ALDH1A1 (0.53) ALDH1A1MAPK1L3MBTL1EPHX1MEN1
SCHEMBL7690148 0.92 ALDH1A1 (0.56) ALDH1A1MAPK1L3MBTL1KMT2ACYP2C19
SCHEMBL16321255 0.83 EPHX2 (0.52) ALDH1A1KMT2ACYP2C19SMN1; SMN2NPC1
SCHEMBL522278 0.81 FABP7 (0.54) ALDH1A1EPHX1MEN1KMT2ATSHR
SCHEMBL31518977 0.81 FABP7 (0.54) ALDH1A1EPHX1MEN1KMT2ATSHR
SCHEMBL24376203 0.81 ALDH1A1 (0.50) ALDH1A1MAPK1L3MBTL1EPHX1MEN1
SCHEMBL2703515 0.79 FABP7 (0.55) ALDH1A1MAPK1L3MBTL1KMT2AGAA
SCHEMBL3706643 0.79 L3MBTL1 (0.51) ALDH1A1MAPK1L3MBTL1KMT2ACYP2C19
SCHEMBL20023111 0.78 MEN1 (0.49) ALDH1A1EPHX1MEN1KMT2ACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6376521-B1 ANTIINFLAMMATORY AGENTS; ANTIISCHEMIC AGENTS; CENTRAL NERVOUS SYSTEM DISORDERS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES 2002-04-23 US disclosed
WO-2000002861-A1 A3 ADENOSINE RECEPTOR ANTAGONISTS THE UNITED STATES OF AMERICA, REPRESENTED BY SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2000-01-20 WO disclosed