Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702691 | 0.93 | HPGD (0.43) | HPGDALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL7701529 | 0.82 | POLB (0.52) | HPGDALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL7700069 | 0.82 | KDM4E (0.45) | HPGDALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL7704549 | 0.80 | ALDH1A1 (0.39) | HPGDALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL7698850 | 0.77 | GPBAR1 (0.39) | HPGDALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL7695160 | 0.77 | MAPT (0.41) | HPGDALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL7700374 | 0.76 | ALDH1A1 (0.32) | HPGDALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7698049 | 0.75 | ALDH1A1 (0.57) | HPGDALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL7695167 | 0.75 | MAPT (0.40) | HPGDALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL7699568 | 0.74 | GPBAR1 (0.44) | HPGDALDH1A1MAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |