Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702691 | 0.86 | HPGD (0.43) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL7695167 | 0.85 | MAPT (0.40) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL7700372 | 0.80 | HPGD (0.41) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL7704094 | 0.79 | MAPT (0.44) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL7693804 | 0.78 | IKBKB (0.45) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL7700069 | 0.78 | KDM4E (0.45) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL7695157 | 0.78 | IKBKB (0.48) | ALDH1A1MAPTKMT2AHPGDKDM4E | |
| SCHEMBL7705474 | 0.77 | IKBKB (0.42) | ALDH1A1MAPTHPGDKDM4ELMNA | |
| SCHEMBL7694123 | 0.77 | KDM4E (0.53) | ALDH1A1MAPTKMT2AHPGDKDM4E | |
| SCHEMBL7704553 | 0.76 | IKBKB (0.34) | ALDH1A1KMT2AHPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |