SCHEMBL7700407

SCHEMBL7700407

O=C1NS(=O)(=O)c2cccc3cccc1c23

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 7/20 0.63
CA9 Q16790 7/20 0.63
CA1 P00915 5/20 0.63
CA2 P00918 5/20 0.63
CA7 P43166 4/20 0.63
CA4 P22748 3/20 0.63
BCHE P06276 2/20 0.63
KDM4E B2RXH2 1/20 0.63
USP2 O75604 1/20 0.63
LMNA P02545 1/20 0.63
CA6 P23280 1/20 0.63
CA5A P35218 1/20 0.63
KMT2A Q03164 1/20 0.63
CA14 Q9ULX7 1/20 0.63
CA5B Q9Y2D0 1/20 0.63
PARP1 P09874 2/20 0.52
RET P07949 2/20 0.47
GRK5 P34947 2/20 0.47
TYRO3 Q06418 2/20 0.47
DYRK1B Q9Y463 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Saccharin SCHEMBL4199164 0.78 CA12 (1.00) CA12CA9CA1CA2CA7
Saccharin SCHEMBL29191365 0.78 CA12 (1.00) CA12CA9CA1CA2CA7
Saccharin SCHEMBL3816 0.78 CA12 (1.00) CA12CA9CA1CA2CA7
Saccharin SCHEMBL4777123 0.78 CA12 (1.00) CA12CA9CA1CA2CA7
Saccharin SCHEMBL6049140 0.78 CA12 (1.00) CA12CA9CA1CA2CA7
Saccharin SCHEMBL29358404 0.78 CA12 (1.00) CA12CA9CA1CA2CA7
Saccharin SCHEMBL7073018 0.78 CA12 (1.00) CA12CA9CA1CA2CA7
Saccharin SCHEMBL6033672 0.78 CA12 (1.00) CA12CA9CA1CA2CA7
Saccharin SCHEMBL588640 0.78 CA12 (1.00) CA12CA9CA1CA2CA7
Saccharin SCHEMBL2526712 0.76 CA12 (0.96) CA12CA9CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11774853-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-10-03 US disclosed
US-20200241414-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-30 US disclosed
US-6346526-B1 CARBAPENICILLIN WITH 1,1-DIOXO-2,3-DIHYDRONAPHTHO(1,8-DE)(1,2)THIAZIN-2-YL-SUBSTITUENT; TREATING STAPHYLOCOCCUS INFECTIONS RESISTANT TO METHICILLIN; SIDE EFFECT REDUCTION MERCK & CO., INC. 2002-02-12 US disclosed
EP-0001290-B1 SUBSTITUTED 2,3-DIHYDROBENZ-(D)-ISOTHIAZOLE-1,1-DIOXIDES AND 2,3-DIHYDRONAPHTHO-(1,8-DE)-1,2-THIAZINE-1,1-DIOXIDES POLAROID CORPORATION (US) 1984-06-27 EP disclosed
US-4359574-A Thiazine-1,1-dioxide and isothiazole-1,1-dioxide derivatives POLAROID CORPORATION (US) 1982-11-16 US disclosed
US-4311839-A Benzisothiazole and naphtho-1,2-thiazine compounds POLAROID CORPORATION (US) 1982-01-19 US disclosed
US-4283537-A Thiazine-1,1-dioxide and isothiazole-1,1-dioxide derivatives and process for preparation POLAROID CORPORATION (US) 1981-08-11 US disclosed
US-4259493-A INDICATOR DYES OR PHOTOGRAPHIC LIGHT-SCREENING DYES POLAROID CORPORATION (US) 1981-03-31 US disclosed
US-4259498-A Process for preparing benzisothiazole-1,1-dioxide and naphtho-1,2-thiazine-1,1-dioxide compounds POLAROID CORPORATION (US) 1981-03-31 US disclosed
US-4255578-A Synthesis of perhalomethylcarbinol-substituted phenol and naphthol sulfamphthalein dyes from the corresponding triacylated derivatives POLAROID CORPORATION (US) 1981-03-10 US disclosed
US-4231929-A Sulfam(na)phthaleins POLAROID CORPORATION (US) 1980-11-04 US disclosed
US-4228075-A Novel sulfam(na)phthaleins POLAROID CORPORATION (US) 1980-10-14 US disclosed
US-4210752-A Synthesis of substituted sulfam(na)phthaleins POLAROID CORPORATION (US) 1980-07-01 US disclosed
US-4204061-A Sulfam(na)phthaleins POLAROID CORPORATION (US) 1980-05-20 US disclosed
US-4195180-A Sulfam (na) phthaleins POLAROID CORPORATION (US) 1980-03-25 US disclosed
US-4191689-A Benzisothiazole-1,1-dioxide and naphtho-1,2-thiazine-1,1-dioxide compounds POLAROID CORPORATION (US) 1980-03-04 US disclosed
US-4186001-A IRREVERSIBLE CLEAVAGE IN ALKALINE SOLUTION TO FORM COLORLESS COMPOUND POLAROID CORPORATION (US) 1980-01-29 US disclosed
US-4178446-A Sulfam(na)phthaleins POLAROID CORPORATION (US) 1979-12-11 US disclosed
US-4178447-A Novel synthesis of 3,3-substituted dihydrobenzisothiazole-1,1-dioxides and -2,3-dihydronaphtho-1,2-thiazine-1,1-dioxides POLAROID CORPORATION (US) 1979-12-11 US disclosed
EP-0001290-A1 Substituted 2,3-dihydrobenz-(d)-isothiazole-1,1-dioxides and 2,3-dihydronaphtho-(1,8-de)-1,2-thiazine-1,1-dioxides POLAROID CORPORATION (US) 1979-04-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200241414-A1 RESIST COMPOSITION AND PATTERNING PROCESS INSR, HNRNPU, HNRNPR CA12 2165/4885CA9 1249/4885CA1 2684/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.