Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.47 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | ITGAV | P06756 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TYMS | P04818 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7414437 | 0.96 | ITGB3 (0.47) | ITGB3ITGA2BITGB1ITGA5PPARG | |
| SCHEMBL7421304 | 0.91 | ITGB3 (0.49) | ITGB3ITGA2BITGB1ITGA5PPARG | |
| SCHEMBL7409546 | 0.91 | ITGB3 (0.51) | ITGB3ITGA2BITGB1ITGA5PPARG | |
| SCHEMBL7423110 | 0.89 | ITGB3 (0.48) | ITGB3ITGA2BITGB1ITGA5PPARG | |
| SCHEMBL7418686 | 0.88 | ITGB1 (0.51) | ITGB3ITGA2BITGB1ITGA5PPARG | |
| Trifluoroacetic Acid SCHEMBL7417323 | 0.87 | ITGB1 (0.47) | ITGB3ITGA2BITGB1ITGA5PPARG | |
| SCHEMBL7414443 | 0.87 | ITGB1 (0.39) | ITGB3ITGA2BITGB1ITGA5PPARG | |
| Trifluoroacetic Acid SCHEMBL7415114 | 0.87 | ITGB3 (0.47) | ITGB3ITGA2BITGB1ITGA5PPARG | |
| SCHEMBL7410553 | 0.86 | ITGB3 (0.50) | ITGB3ITGA2BITGB1ITGA5PPARG | |
| SCHEMBL7411715 | 0.85 | ITGB3 (0.51) | ITGB3ITGA2BITGB1ITGA5PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6344484-B1 | TREATMENT OF TUMOR GROWTH, METASTASIS, OSTEOPOROSIS, RESTENOSIS, INFLAMMATION, MACULAR DEGENERATION, DIABETIC RETINOPATHY, AND RHEUMATOID ARTHRITIS | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2002-02-05 | — | — | US | claimed |