Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | TYMP | P19971 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528998 | 0.94 | SORT1 (0.59) | SORT1RAB9ANPC1CYP1A2CYP2C19 | |
| SCHEMBL11866619 | 0.82 | SORT1 (0.47) | SORT1HSD17B10MTNR1AMTNR1BMAPT | |
| SCHEMBL8911113 | 0.77 | — | — | |
| SCHEMBL7705718 | 0.77 | ALDH1A1 (0.53) | HSD17B10MTNR1BMAPTMEN1ALDH1A1 | |
| SCHEMBL21144227 | 0.76 | ALDH1A1 (0.51) | MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL27034270 | 0.73 | SORT1 (0.49) | SORT1MTNR1AMTNR1BTSHR | |
| SCHEMBL26616575 | 0.72 | DAO (0.50) | SORT1RAB9ANPC1NOTUMMEN1 | |
| SCHEMBL19533904 | 0.68 | SORT1 (0.67) | SORT1MTNR1AMTNR1BNOTUMTSHR | |
| SCHEMBL21961217 | 0.68 | SORT1 (0.61) | SORT1MTNR1AMTNR1BNOTUMALDH1A1 | |
| SCHEMBL1063939 | 0.68 | MAPT (0.52) | RAB9ANPC1CYP1A2CYP2C19MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002079176-A1 | PROCESS FOR 2,4-DISUBSTITUTED-1,3,4-OXADIAZOLINE-5-THIONE AND 5-ONE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2002-10-10 | — | — | WO | disclosed |