Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700452 | 1.00 | SLC6A9 (0.53) | SLC6A9SIGMAR1OPRK1SLC6A4MTNR1A | |
| Hydrochloric Acid SCHEMBL7709388 | 0.86 | SLC6A9 (0.72) | SLC6A9SIGMAR1OPRK1MTNR1AMTNR1B | |
| SCHEMBL7703449 | 0.86 | SLC6A9 (0.48) | SLC6A9SIGMAR1SLC6A4MTNR1AMTNR1B | |
| SCHEMBL7703453 | 0.86 | SLC6A9 (0.48) | SLC6A9SIGMAR1SLC6A4MTNR1AMTNR1B | |
| SCHEMBL7703450 | 0.86 | SLC6A9 (0.48) | SLC6A9SIGMAR1SLC6A4MTNR1AMTNR1B | |
| SCHEMBL7703310 | 0.86 | SLC6A9 (0.56) | SLC6A9OPRK1SLC6A4MTNR1AMTNR1B | |
| SCHEMBL7702711 | 0.86 | SLC6A9 (0.56) | SLC6A9OPRK1SLC6A4MTNR1AMTNR1B | |
| SCHEMBL7700175 | 0.84 | SLC6A9 (0.75) | SLC6A9 | |
| SCHEMBL7704292 | 0.84 | SLC6A9 (0.75) | SLC6A9 | |
| SCHEMBL7698359 | 0.83 | SLC6A4 (0.55) | SLC6A9SIGMAR1SLC6A4MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100769-B1 | AMINOMETHYLCARBOXYLIC ACID DERIVATIVES | AKZO NOBEL NV (NL) | 2002-12-04 | — | — | EP | disclosed |
| US-6410592-B1 | THERAPY FOR CENTRAL NERVOUS SYSTEM DISORDERS, PSYCHOLOGICAL DISORDERS | AKZO NOBEL N.V. (NL) | 2002-06-25 | — | — | US | disclosed |