Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 6/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | MLNR | O43193 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702711 | 1.00 | SLC6A9 (0.56) | SLC6A9ESR1ESR2STSHSD17B1 | |
| SCHEMBL7700451 | 0.86 | SLC6A9 (0.53) | SLC6A9HTR2AHTR2CSLC6A4OPRK1 | |
| SCHEMBL7700452 | 0.86 | SLC6A9 (0.53) | SLC6A9HTR2AHTR2CSLC6A4OPRK1 | |
| SCHEMBL7701273 | 0.84 | SLC6A9 (0.60) | SLC6A9HRH1HRH3 | |
| SCHEMBL7703437 | 0.84 | SLC6A9 (0.60) | SLC6A9HRH1HRH3 | |
| SCHEMBL7704292 | 0.84 | SLC6A9 (0.75) | SLC6A9 | |
| SCHEMBL7700175 | 0.84 | SLC6A9 (0.75) | SLC6A9 | |
| SCHEMBL7698359 | 0.83 | SLC6A4 (0.55) | SLC6A9DRD2DRD3SLC6A2SLC6A4 | |
| SCHEMBL7703450 | 0.80 | SLC6A9 (0.48) | SLC6A9SLC6A4MTNR1AMTNR1B | |
| SCHEMBL7703453 | 0.80 | SLC6A9 (0.48) | SLC6A9SLC6A4MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100769-B1 | AMINOMETHYLCARBOXYLIC ACID DERIVATIVES | AKZO NOBEL NV (NL) | 2002-12-04 | — | — | EP | disclosed |
| US-6410592-B1 | THERAPY FOR CENTRAL NERVOUS SYSTEM DISORDERS, PSYCHOLOGICAL DISORDERS | AKZO NOBEL N.V. (NL) | 2002-06-25 | — | — | US | disclosed |