Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.55 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7709036 | 0.87 | SLC6A9 (0.68) | SLC6A4SLC6A9DRD2DRD3SIGMAR1 | |
| SCHEMBL7703310 | 0.83 | SLC6A9 (0.56) | SLC6A4SLC6A9DRD2DRD3MTNR1A | |
| SCHEMBL7702711 | 0.83 | SLC6A9 (0.56) | SLC6A4SLC6A9DRD2DRD3MTNR1A | |
| SCHEMBL7700452 | 0.83 | SLC6A9 (0.53) | SLC6A4SLC6A9SIGMAR1MTNR1AMTNR1B | |
| SCHEMBL7700451 | 0.83 | SLC6A9 (0.53) | SLC6A4SLC6A9SIGMAR1MTNR1AMTNR1B | |
| SCHEMBL7704292 | 0.81 | SLC6A9 (0.75) | SLC6A9 | |
| SCHEMBL7700175 | 0.81 | SLC6A9 (0.75) | SLC6A9 | |
| SCHEMBL7703437 | 0.80 | SLC6A9 (0.60) | SLC6A9KDM1AMAOAMAOB | |
| SCHEMBL7701273 | 0.80 | SLC6A9 (0.60) | SLC6A9KDM1AMAOAMAOB | |
| SCHEMBL7698356 | 0.77 | MTNR1A (0.40) | SLC6A4SLC6A9DRD2DRD3MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100769-B1 | AMINOMETHYLCARBOXYLIC ACID DERIVATIVES | AKZO NOBEL NV (NL) | 2002-12-04 | — | — | EP | disclosed |
| US-6410592-B1 | THERAPY FOR CENTRAL NERVOUS SYSTEM DISORDERS, PSYCHOLOGICAL DISORDERS | AKZO NOBEL N.V. (NL) | 2002-06-25 | — | — | US | disclosed |